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A molecular defect in thrombasthenic platelets.

An IgG antibody found in the serum of a thrombasthenic patient reacted in complement fixation with platelets from 350 normal individuals but was nonreactive with platelets from eight other thrombasthenic patients. ADP-induced aggregation of normal platelets was inhibited by the patient's antibody. F...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Degos, L, Dautigny, A, Brouet, J C, Colombani, M, Ardaillou, N, Caen, J P, Colombani, J
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1975
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436575/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1141437/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108074
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