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TACC3–ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation

The interaction between TACC3 (transforming acidic coiled coil protein 3) and the microtubule polymerase ch-TOG (colonic, hepatic tumor overexpressed gene) is evolutionarily conserved. Loading of TACC3–ch-TOG onto mitotic spindle microtubules requires the phosphorylation of TACC3 by Aurora-A kinase...

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Bibliografiske detaljer
Udgivet i:Biol Open
Main Authors: Gutiérrez-Caballero, Cristina, Burgess, Selena G., Bayliss, Richard, Royle, Stephen J.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365485/
https://ncbi.nlm.nih.gov/pubmed/25596274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.201410843
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