CXCR3 Chemokine Receptor Enables Local CD8(+) T Cell Migration for the Destruction of Virus-Infected Cells

CD8(+) T cells play a critical role limiting peripheral virus replication, yet how they locate virus-infected cells within tissues is unknown. Here, we have examined the environmental signals that CD8(+) T cells use to localize and eliminate virus-infected skin cells. Epicutaneous vaccinia virus (VV...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Hickman, Heather D., Reynoso, Glennys V., Ngudiankama, Barbara F., Cush, Stephanie S., Gibbs, James, Bennink, Jack R., Yewdell, Jonathan W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365427/
https://ncbi.nlm.nih.gov/pubmed/25769612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.02.009
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