Improving the Sensitivity of the Xpert MTB/RIF Assay on Sputum Pellets by Decreasing the Amount of Added Sample Reagent: a Laboratory and Clinical Evaluation

The Xpert MTB/RIF (Xpert) assay permits rapid near-patient detection of Mycobacterium tuberculosis in sputum; however, the test sensitivity remains suboptimal in paucibacillary specimens that are negative for acid-fast bacilli using smear microscopy. Xpert testing includes dilution with sample reage...

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Dades bibliogràfiques
Publicat a:J Clin Microbiol
Autors principals: Dharan, Nila J., Amisano, Danielle, Mboowa, Gerald, Ssengooba, Willy, Blakemore, Robert, Kubiak, Rachel W., Armstrong, Derek T., Jones, Martin, Manabe, Yukari C., Joloba, Moses L., Ellner, Jerrold J., Dorman, Susan E., Alland, David
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Mycobacteriology and Aerobic Actinomycetes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365264/
https://ncbi.nlm.nih.gov/pubmed/25653410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.03619-14
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