Improving the Sensitivity of the Xpert MTB/RIF Assay on Sputum Pellets by Decreasing the Amount of Added Sample Reagent: a Laboratory and Clinical Evaluation

The Xpert MTB/RIF (Xpert) assay permits rapid near-patient detection of Mycobacterium tuberculosis in sputum; however, the test sensitivity remains suboptimal in paucibacillary specimens that are negative for acid-fast bacilli using smear microscopy. Xpert testing includes dilution with sample reage...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: Dharan, Nila J., Amisano, Danielle, Mboowa, Gerald, Ssengooba, Willy, Blakemore, Robert, Kubiak, Rachel W., Armstrong, Derek T., Jones, Martin, Manabe, Yukari C., Joloba, Moses L., Ellner, Jerrold J., Dorman, Susan E., Alland, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Mycobacteriology and Aerobic Actinomycetes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365264/
https://ncbi.nlm.nih.gov/pubmed/25653410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.03619-14
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