ARA 290, a Nonerythropoietic Peptide Engineered from Erythropoietin, Improves Metabolic Control and Neuropathic Symptoms in Patients with Type 2 Diabetes

Although erythropoietin ameliorates experimental type 2 diabetes with neuropathy, serious side effects limit its potential clinical use. ARA 290, a nonhematopoietic peptide designed from the structure of erythropoietin, interacts selectively with the innate repair receptor that mediates tissue prote...

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Veröffentlicht in:Mol Med
Hauptverfasser: Brines, Michael, Dunne, Ann N, van Velzen, Monique, Proto, Paolo L, Ostenson, Claes-Goran, Kirk, Rita I, Petropoulos, Ioannis N, Javed, Saad, Malik, Rayaz A, Cerami, Anthony, Dahan, Albert
Format: Artigo
Sprache:Inglês
Veröffentlicht: ScholarOne 2015
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365069/
https://ncbi.nlm.nih.gov/pubmed/25387363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2014.00215
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