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Progesterone and Wnt4 control mammary stem cells via myoepithelial crosstalk
Ovarian hormones increase breast cancer risk by poorly understood mechanisms. We assess the role of progesterone on global stem cell function by serially transplanting mouse mammary epithelia. Progesterone receptor (PR) deletion severely reduces the regeneration capacity of the mammary epithelium. T...
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| Publicado en: | EMBO J |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BlackWell Publishing Ltd
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4365033/ https://ncbi.nlm.nih.gov/pubmed/25603931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490434 |
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