लोड हो रहा है...
Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage
Aging and carcinogenesis coincide with the accumulation of DNA damage and mutations in stem and progenitor cells. Molecular mechanisms that influence responses of stem and progenitor cells to DNA damage remain to be delineated. Here, we show that niche positioning and Wnt signaling activity modulate...
में बचाया:
| में प्रकाशित: | EMBO J |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
BlackWell Publishing Ltd
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4365032/ https://ncbi.nlm.nih.gov/pubmed/25609789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490700 |
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