Combined Antigen-Specific Interferon-γ and Interleukin-2 Release Assay (FluoroSpot) for the Diagnosis of Mycobacterium tuberculosis Infection

BACKGROUND: To evaluate interleukin (IL)-2 and interferon (IFN)-γ secreting T-cells in parallel for the differentiation of latent infection with Mycobacterium tuberculosis infection (LTBI) from active tuberculosis. METHODS: Following ex-vivo stimulation of peripheral blood mononuclear cells (PBMC) w...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chesov, Dumitru, Lange, Christoph, Daduna, Franziska, Crudu, Valeriu, Preyer, Rosemarie, Ernst, Martin, Kalsdorf, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364905/
https://ncbi.nlm.nih.gov/pubmed/25785445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120006
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