Human Malignant Melanoma-Derived Progestagen-Associated Endometrial Protein Immunosuppresses T Lymphocytes In Vitro

Progestagen-associated endometrial protein (PAEP) is a glycoprotein of the lipocalin family that acts as a negative regulator of T cell receptor-mediated activation. However, the function of tumor-derived PAEP on the human immune system in the tumor microenvironment is unknown. PAEP is highly expres...

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Veröffentlicht in:PLoS One
Hauptverfasser: Ren, Suping, Chai, Lina, Wang, Chunyan, Li, Changlan, Ren, Qiquan, Yang, Lihua, Wang, Fumei, Qiao, Zhixin, Li, Weijing, He, Min, Riker, Adam I., Han, Ying, Yu, Qun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364885/
https://ncbi.nlm.nih.gov/pubmed/25785839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119038
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