Prioritizing Therapeutics for Lung Cancer: An Integrative Meta-analysis of Cancer Gene Signatures and Chemogenomic Data

Repurposing FDA-approved drugs with the aid of gene signatures of disease can accelerate the development of new therapeutics. A major challenge to developing reliable drug predictions is heterogeneity. Different gene signatures of the same disease or drug treatment often show poor overlap across stu...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Fortney, Kristen, Griesman, Joshua, Kotlyar, Max, Pastrello, Chiara, Angeli, Marc, Sound-Tsao, Ming, Jurisica, Igor
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364883/
https://ncbi.nlm.nih.gov/pubmed/25786242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004068
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