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Starvation-induced MTMR13 and RAB21 activity regulates VAMP8 to promote autophagosome–lysosome fusion
Autophagy, the process for recycling cytoplasm in the lysosome, depends on membrane trafficking. We previously identified Drosophila Sbf as a Rab21 guanine nucleotide exchange factor (GEF) that acts with Rab21 in endosomal trafficking. Here, we show that Sbf/MTMR13 and Rab21 have conserved functions...
Gespeichert in:
| Veröffentlicht in: | EMBO Rep |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BlackWell Publishing Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4364869/ https://ncbi.nlm.nih.gov/pubmed/25648148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439464 |
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