Green Tea Polyphenol (−)-Epigallocatechin-3-Gallate Restores Nrf2 Activity and Ameliorates Crescentic Glomerulonephritis

Crescentic glomerulonephritis (GN) is the most severe form of GN and is associated with significant morbidity and mortality despite aggressive immunotherapy with steroids, cytotoxic drugs, and plasmapheresis. We examined the therapeutic efficacy of the green tea polyphenol (−)-epigallocatechin-3-gal...

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Udgivet i:PLoS One
Main Authors: Ye, Ting, Zhen, Junhui, Du, Yong, Zhou, Jason K., Peng, Ai, Vaziri, Nosratola D., Mohan, Chandra, Xu, Yan, Zhou, Xin J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364748/
https://ncbi.nlm.nih.gov/pubmed/25785827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119543
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