Pro-Arrhythmic Potential of Oral Antihistamines (H1): Combining Adverse Event Reports with Drug Utilization Data across Europe

BACKGROUND: There is appreciable utilisation of antihistamines (H(1)) in European countries, either prescribed by physician and purchased by patients for self-medication. Terfenadine and astemizole underwent regulatory restrictions in ’90 because of their cardiac toxicity, but only scarce clinical d...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Poluzzi, Elisabetta, Raschi, Emanuel, Godman, Brian, Koci, Ariola, Moretti, Ugo, Kalaba, Marija, Wettermark, Bjorn, Sturkenboom, Miriam, De Ponti, Fabrizio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364720/
https://ncbi.nlm.nih.gov/pubmed/25785934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119551
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