Deregulation of microRNAs Let-7a and miR-21 mediate aberrant STAT3 signaling during human papillomavirus-induced cervical carcinogenesis: role of E6 oncoprotein

BACKGROUND: Aberrantly expressed and constitutively active STAT3 signaling plays a pivotal role in initiation and progression of human papillomavirus-induced cervical carcinogenesis. However, the underlying mechanism(s) responsible for pleiotropic effects of STAT3 signaling is poorly understood. In...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Shishodia, Gauri, Verma, Gaurav, Srivastava, Yogesh, Mehrotra, Ravi, Das, Bhudev Chandra, Bharti, Alok Chandra
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364636/
https://ncbi.nlm.nih.gov/pubmed/25539644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-996
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