Root of Polygonum cuspidatum extract reduces progression of diabetes-induced mesangial cell dysfunction via inhibition of platelet-derived growth factor-BB (PDGF-BB) and interaction with its receptor in streptozotocin-induced diabetic rats

BACKGROUND: Platelet-derived growth factor–BB (PDGF-BB) is highly expressed in the renal tissues of patients with diabetic nephropathy, and it plays an important role in the initiation and progression of diabetic nephropathy. The aim of this study was to evaluate the protective effects of root of Po...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Complement Altern Med
Prif Awduron: Sohn, Eunjin, Kim, Junghyun, Kim, Chan-Sik, Jo, Kyuhyung, Lee, Yun Mi, Kim, Jin Sook
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364577/
https://ncbi.nlm.nih.gov/pubmed/25495844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-14-477
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