Root of Polygonum cuspidatum extract reduces progression of diabetes-induced mesangial cell dysfunction via inhibition of platelet-derived growth factor-BB (PDGF-BB) and interaction with its receptor in streptozotocin-induced diabetic rats

BACKGROUND: Platelet-derived growth factor–BB (PDGF-BB) is highly expressed in the renal tissues of patients with diabetic nephropathy, and it plays an important role in the initiation and progression of diabetic nephropathy. The aim of this study was to evaluate the protective effects of root of Po...

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Bibliographic Details
Published in:BMC Complement Altern Med
Main Authors: Sohn, Eunjin, Kim, Junghyun, Kim, Chan-Sik, Jo, Kyuhyung, Lee, Yun Mi, Kim, Jin Sook
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364577/
https://ncbi.nlm.nih.gov/pubmed/25495844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-14-477
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