Root of Polygonum cuspidatum extract reduces progression of diabetes-induced mesangial cell dysfunction via inhibition of platelet-derived growth factor-BB (PDGF-BB) and interaction with its receptor in streptozotocin-induced diabetic rats

BACKGROUND: Platelet-derived growth factor–BB (PDGF-BB) is highly expressed in the renal tissues of patients with diabetic nephropathy, and it plays an important role in the initiation and progression of diabetic nephropathy. The aim of this study was to evaluate the protective effects of root of Po...

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Vydáno v:BMC Complement Altern Med
Hlavní autoři: Sohn, Eunjin, Kim, Junghyun, Kim, Chan-Sik, Jo, Kyuhyung, Lee, Yun Mi, Kim, Jin Sook
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364577/
https://ncbi.nlm.nih.gov/pubmed/25495844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-14-477
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