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Defining CD4 T Cell Memory by the Epigenetic Landscape of CpG DNA Methylation

Memory T cells are primed for rapid responses to antigen; however, the molecular mechanisms responsible for priming remain incompletely defined. CpG methylation in promoters is an epigenetic modification, which regulates gene transcription. Using targeted bisulfite sequencing, we examined methylatio...

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Detalles Bibliográficos
Publicado en:J Immunol
Main Authors: Komori, H. Kiyomi, Hart, Traver, LaMere, Sarah A., Chew, Pamela V., Salomon, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364524/
https://ncbi.nlm.nih.gov/pubmed/25576597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401162
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