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Immunological loss-of-function due to genetic gain-of-function in humans: autosomal dominance of the third kind
All the human primary immunodeficiencies (PIDs) recognized as such in the 1950s were Mendelian traits and, whether autosomal or X-linked, displayed recessive inheritance. The first autosomal dominant (AD) PID, hereditary angioedema, was recognized in 1963. However, since the first identification of...
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| Publicado no: | Curr Opin Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4364384/ https://ncbi.nlm.nih.gov/pubmed/25645939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2015.01.005 |
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