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Insertion/deletion polymorphism of the angiotensin-converting enzyme gene is strongly associated with coronary heart disease in non-insulin-dependent diabetes mellitus.

Non-insulin-dependent diabetes mellitus (NIDDM) is considered a model of premature atherosclerosis with a strong genetic component. We have investigated the role of angiotensin-converting enzyme (ACE; EC 3.4.15.1) gene in 316 unrelated NIDDM individuals, 132 who had myocardial infarction or signific...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Ruiz, J, Blanché, H, Cohen, N, Velho, G, Cambien, F, Cohen, D, Passa, P, Froguel, P
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43641/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8170965/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.9.3662
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