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Functionally active targeting domain of the beta-adrenergic receptor kinase: an inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase.

The beta-adrenergic receptor kinase (beta ARK) phosphorylates its membrane-associated receptor substrates, such as the beta-adrenergic receptor, triggering events leading to receptor desensitization. beta ARK activity is markedly stimulated by the isoprenylated beta gamma subunit complex of heterotr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Inglese, J, Luttrell, L M, Iñiguez-Lluhi, J A, Touhara, K, Koch, W J, Lefkowitz, R J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43636/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8170960/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.9.3637
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