Combined Epidermal Growth Factor Receptor and Beclin1 Autophagic Protein Expression Analysis Identifies Different Clinical Presentations, Responses to Chemo- and Radiotherapy, and Prognosis in Glioblastoma

Dysregulated EGFR in glioblastoma may inactivate the key autophagy protein Beclin1. Each of high EGFR and low Beclin1 protein expression, independently, has been associated with tumor progression and poor prognosis. High (H) compared to low (L) expression of EGFR and Beclin1 is here correlated with...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Tini, Paolo, Belmonte, Giuseppe, Toscano, Marzia, Miracco, Clelia, Palumbo, Silvia, Pastina, Pierpaolo, Battaglia, Giuseppe, Nardone, Valerio, Butorano, Marie Aimée Gloria Munezero, Masucci, Armando, Cerase, Alfonso, Pirtoli, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363549/
https://ncbi.nlm.nih.gov/pubmed/25821789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/208076
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