IRGM3 Contributes to Immunopathology and Is Required for Differentiation of Antigen-Specific Effector CD8(+) T Cells in Experimental Cerebral Malaria

Gamma interferon (IFN-γ) drives antiparasite responses and immunopathology during infection with Plasmodium species. Immunity-related GTPases (IRGs) are a class of IFN-γ-dependent proteins that are essential for cell autonomous immunity to numerous intracellular pathogens. However, it is currently u...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Guo, Jintao, McQuillan, James A., Yau, Belinda, Tullo, Gregory S., Long, Carole A., Bertolino, Patrick, Roediger, Ben, Weninger, Wolfgang, Taylor, Gregory A., Hunt, Nicholas H., Ball, Helen J., Mitchell, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363434/
https://ncbi.nlm.nih.gov/pubmed/25644000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02701-14
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