Blocking Yersiniabactin Import Attenuates Extraintestinal Pathogenic Escherichia coli in Cystitis and Pyelonephritis and Represents a Novel Target To Prevent Urinary Tract Infection

The emergence and spread of extended-spectrum beta-lactamases and carbapenemases among common bacterial pathogens are threatening our ability to treat routine hospital- and community-acquired infections. With the pipeline for new antibiotics virtually empty, there is an urgent need to develop novel...

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Udgivet i:Infect Immun
Main Authors: Brumbaugh, Ariel R., Smith, Sara N., Subashchandrabose, Sargurunathan, Himpsl, Stephanie D., Hazen, Tracy H., Rasko, David A., Mobley, Harry L. T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Bacterial Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363403/
https://ncbi.nlm.nih.gov/pubmed/25624354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02904-14
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