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Adaptive Resistance in Bacteria Requires Epigenetic Inheritance, Genetic Noise, and Cost of Efflux Pumps

Adaptive resistance emerges when populations of bacteria are subjected to gradual increases of antibiotics. It is characterized by a rapid emergence of resistance and fast reversibility to the non-resistant phenotype when the antibiotic is removed from the medium. Recent work shows that adaptive res...

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Publicat a:PLoS One
Autors principals: Motta, Santiago Sandoval, Cluzel, Philippe, Aldana, Maximino
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363326/
https://ncbi.nlm.nih.gov/pubmed/25781931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118464
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