Prognostic Significance of Active and Modified forms of Endothelin 1 in Patients with Heart Failure with Reduced Ejection Fraction

OBJECTIVES: Concentrations of endothelin I (ET1) are elevated in CHF patients, and, like other biomarkers that reflect hemodynamic status and cardiac pathophysiology, are prognostic. The Singulex assay (Sgx-ET1) measures the active form of ET1, with a short in-vivo half-life and C-terminal endotheli...

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Pubblicato in:Clin Biochem
Autori principali: Gottlieb, Stephen S., Harris, Kristie, Todd, John, Estis, Joel, Christenson, Robert H., Torres, Victoria, Whittaker, Kerry, Rebuck, Heather, Wawrzyniak, Andrew, Krantz, David S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363211/
https://ncbi.nlm.nih.gov/pubmed/25541019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clinbiochem.2014.12.012
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