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Integrating B cell lineage information into statistical tests for detecting selection in Ig sequences()
Detecting selection in B cell immunoglobulin (Ig) sequences is critical to understanding affinity maturation, and can provide insights into antigen-driven selection in normal and pathologic immune responses. The most common sequence-based methods for detecting selection analyze the ratio of replacem...
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| Vydáno v: | J Immunol |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4363135/ https://ncbi.nlm.nih.gov/pubmed/24376267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301551 |
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