D-enantiomeric peptides that eradicate wild-type and multi-drug resistant biofilms and protect against lethal Pseudomonas aeruginosa infections

In many infections, bacteria form surface-associated communities known as biofilms that are substantially more resistant to antibiotics than their planktonic counterparts. Based on the design features of active anti-biofilm peptides, we made a series of related 12-amino acid L-, D- and retro-inverso...

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Dettagli Bibliografici
Pubblicato in:Chem Biol
Autori principali: de la Fuente-Núñez, César, Reffuveille, Fany, Mansour, Sarah C., Reckseidler-Zenteno, Shauna L., Hernández, Diego, Brackman, Gilles, Coenye, Tom, Hancock, Robert E.W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362967/
https://ncbi.nlm.nih.gov/pubmed/25699603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.01.002
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