Blood–brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment

BACKGROUND: Functional loss of blood–brain barrier (BBB) is suggested to be pivotal to pathogenesis and pathology of vascular-based neurodegenerative disorders such as Alzheimer’s disease. We recently reported in wild-type mice maintained on standard diets, progressive deterioration of capillary fun...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Immun Ageing
Main Authors: Elahy, Mina, Jackaman, Connie, Mamo, John CL, Lam, Virginie, Dhaliwal, Satvinder S, Giles, Corey, Nelson, Delia, Takechi, Ryusuke
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362825/
https://ncbi.nlm.nih.gov/pubmed/25784952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12979-015-0029-9
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki