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EGFR-expression in primary urinary bladder cancer and corresponding metastases and the relation to HER2-expression. On the possibility to target these receptors with radionuclides

BACKGROUND: There is limited effect of tyrosine kinase inhibitors or “naked” antibodies binding EGFR or HER2 for therapy of metastasized urinary bladder cancer and these methods are therefore not routinely used. Targeting radio-nuclides to the extracellular domain of the receptors is potentially a b...

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Detalhes bibliográficos
Publicado no:Radiol Oncol
Main Authors: Carlsson, Jörgen, Wester, Kenneth, De La Torre, Manuel, Malmström, Per-Uno, Gårdmark, Truls
Formato: Artigo
Idioma:Inglês
Publicado em: Versita, Warsaw 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362606/
https://ncbi.nlm.nih.gov/pubmed/25810701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/raon-2014-0015
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