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Aurora B prevents chromosome arm separation defects by promoting telomere dispersion and disjunction
The segregation of centromeres and telomeres at mitosis is coordinated at multiple levels to prevent the formation of aneuploid cells, a phenotype frequently observed in cancer. Mitotic instability arises from chromosome segregation defects, giving rise to chromatin bridges at anaphase. Most of thes...
Guardat en:
| Publicat a: | J Cell Biol |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4362453/ https://ncbi.nlm.nih.gov/pubmed/25778919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201407016 |
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