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Anti-fibrotic effect of Aliskiren in rats with deoxycorticosterone induced myocardial fibrosis and its potential mechanism

The objective of our study was to investigate the effect of Aliskiren, a renin inhibitor, on the deoxycorticosterone (DOCA) induced myocardial fibrosis in a rat model and its underlying mechanism. A total of 45 Sprague-Dawley (SD) rats underwent right nephrectomy and were randomly assigned into 3 gr...

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Bibliografiske detaljer
Udgivet i:Bosn J Basic Med Sci
Main Authors: Ma, Likun, Hua, Jinsheng, He, Lifeng, Li, Qian, Zhou, Junling, Yu, Jiangtao
Format: Artigo
Sprog:Inglês
Udgivet: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362441/
https://ncbi.nlm.nih.gov/pubmed/22642589
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