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Pre-TCRα supports CD3-dependent reactivation and expansion of TCRα-deficient primary human T-cells
Chimeric antigen receptor technology offers a highly effective means for increasing the anti-tumor effects of autologous adoptive T-cell immunotherapy, and could be made widely available if adapted to the use of allogeneic T-cells. Although gene-editing technology can be used to remove the alloreact...
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Udgivet i: | Mol Ther Methods Clin Dev |
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Main Authors: | , , , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Nature Publishing Group
2014
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4362381/ https://ncbi.nlm.nih.gov/pubmed/26015965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2014.21 |
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