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Lentiviral vectors containing mouse Csf1r control elements direct macrophage-restricted expression in multiple species of birds and mammals

The development of macrophages requires signaling through the lineage-restricted receptor Csf1r. Macrophage-restricted expression of transgenic reporters based upon Csf1r requires the highly conserved Fms-intronic regulatory element (FIRE). We have created a lentiviral construct containing mouse FIR...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Pridans, Clare, Lillico, Simon, Whitelaw, Bruce, Hume, David A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362345/
https://ncbi.nlm.nih.gov/pubmed/26015955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2014.10
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