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Ruthenium Polypyridyl Complex Inhibits Growth and Metastasis of Breast Cancer Cells by Suppressing FAK signaling with Enhancement of TRAIL-induced Apoptosis

Ruthenium-based complexes have emerged as promising antitumor and antimetastatic agents during the past decades. However, the limited understanding of the antimetastatic mechanisms of these agents is a roadblock to their clinical application. Herein, we reported that, RuPOP, a ruthenium polypyridyl...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Cao, Wenqiang, Zheng, Wenjie, Chen, Tianfeng
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361883/
https://ncbi.nlm.nih.gov/pubmed/25778692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09157
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