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Effects of Iron Overload on the Bone Marrow Microenvironment in Mice

OBJECTIVE: Using a mouse model, Iron Overload (IO) induced bone marrow microenvironment injury was investigated, focusing on the involvement of reactive oxygen species (ROS). METHODS: Mice were intraperitoneally injected with iron dextran (12.5, 25, or 50mg) every three days for two, four, and six w...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhang, Yuchen, Zhai, Wenjing, Zhao, Mingfeng, Li, Deguan, Chai, Xiao, Cao, Xiaoli, Meng, Juanxia, Chen, Jie, Xiao, Xia, Li, Qing, Mu, Juan, Shen, Jichun, Meng, Aimin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361683/
https://ncbi.nlm.nih.gov/pubmed/25774923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120219
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