CYP2C9 Genotype vs. Metabolic Phenotype for Individual Drug Dosing—A Correlation Analysis Using Flurbiprofen as Probe Drug

Currently, genotyping of patients for polymorphic enzymes responsible for metabolic elimination is considered a possibility to adjust drug dose levels. For a patient to profit from this procedure, the interindividual differences in drug metabolism within one genotype should be smaller than those bet...

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Udgivet i:PLoS One
Main Authors: Vogl, Silvia, Lutz, Roman W., Schönfelder, Gilbert, Lutz, Werner K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361569/
https://ncbi.nlm.nih.gov/pubmed/25775139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120403
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