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Escalation of cocaine consumption in short and long access self-administration procedures

BACKGROUND: Escalation of consumption is a hallmark of cocaine addiction. Many animal models reveal escalation by increasing the duration of drug access (e.g., 6 to 24 h/day) after longer histories of self-administration. We recently developed a method that reveals escalation early post-acquisition...

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Publicat a:Drug Alcohol Depend
Autors principals: Mandt, Bruce H., Copenhagen, Leland I., Zahniser, Nancy R., Allen, Richard M.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361373/
https://ncbi.nlm.nih.gov/pubmed/25697912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2015.01.039
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