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Determination of Variation Parameters as a Crucial Step in Designing TMT-Based Clinical Proteomics Experiments

In quantitative shotgun proteomic analyses by liquid chromatography and mass spectrometry, a rigid study design is necessary in order to obtain statistically relevant results. Hypothesis testing, sample size calculation and power estimation are fundamental concepts that require consideration upon de...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Maes, Evelyne, Valkenborg, Dirk, Baggerman, Geert, Willems, Hanny, Landuyt, Bart, Schoofs, Liliane, Mertens, Inge
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361338/
https://ncbi.nlm.nih.gov/pubmed/25775046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120115
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