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Alveolar-capillary Adaptation to Chronic Hypoxia in the Fatty Lung

AIM: Obese diabetic (ZDF fa/fa) rats with genetic leptin resistance suffer chronic lipotoxicity associated with age-related lung restriction and abnormal alveolar ultrastructure. We hypothesized that these abnormalities impair adaptation to ambient hypoxia. METHODS: Male fa/fa and lean (+/+) ZDF rat...

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Publicado en:Acta Physiol (Oxf)
Main Authors: Yilmaz, Cuneyt, Ravikumar, Priya, Gyawali, Dipendra, Iyer, Roshni, Unger, Roger H., Hsia, Connie C.W.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361300/
https://ncbi.nlm.nih.gov/pubmed/25363080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.12419
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