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Dose Specific Effects of Olanzapine in the Treatment of Alcohol Dependence

RATIONALE: It is well-established that the rewarding effects of alcohol are modulated by the mesolimbic dopaminergic system. Olanzapine, a D2 dopamine antagonist, has been shown to reduce alcohol craving and consumption. OBJECTIVE: To clarify whether olanzapine has clinical utility in the treatment...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: Littlewood, Rae A., Claus, Eric D., Arenella, Pamela, Bogenschutz, Michael, Karoly, Hollis, Feldstein Ewing, Sarah W., Bryan, Angela D., Hutchison, Kent E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361265/
https://ncbi.nlm.nih.gov/pubmed/25304864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-014-3757-1
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