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Tunicamycin-induced Unfolded Protein Response in the Developing Mouse Brain
Accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) causes ER stress, resulting in the activation of the unfolded protein response (UPR). ER stress and UPR are associated with many neurodevelopmental and neurodegenerative disorders. The developing brain is particularly s...
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| Publicado no: | Toxicol Appl Pharmacol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4361256/ https://ncbi.nlm.nih.gov/pubmed/25620058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.12.019 |
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