Viral Infection of Human Lung Macrophages Increases PDL1 Expression via IFNβ

Lung macrophages are an important defence against respiratory viral infection and recent work has demonstrated that influenza-induced macrophage PDL1 expression in the murine lung leads to rapid modulation of CD8+ T cell responses via the PD1 receptor. This PD1/PDL1 pathway may downregulate acute in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Staples, Karl J., Nicholas, Ben, McKendry, Richard T., Spalluto, C. Mirella, Wallington, Joshua C., Bragg, Craig W., Robinson, Emily C., Martin, Kirstin, Djukanović, Ratko, Wilkinson, Tom M. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361055/
https://ncbi.nlm.nih.gov/pubmed/25775126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121527
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