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Spinal nNOS regulates phrenic motor facilitation by a 5-HT(2B) receptor- and NADPH oxidase-dependent mechanism

Acute intermittent hypoxia (AIH) induces phrenic long-term facilitation (pLTF) by a mechanism that requires spinal serotonin (5-HT) receptor activation and NADPH oxidase (NOX) activity. Here, we investigated whether: 1) spinal nitric oxide synthase (NOS) activity is necessary for AIH-induced pLTF; 2...

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Detalhes bibliográficos
Publicado no:Neuroscience
Main Authors: MacFarlane, PM, Vinit, S, Mitchell, GS
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361021/
https://ncbi.nlm.nih.gov/pubmed/24680940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.03.014
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