Characterization of regulatory sequences in alternative promoters of hypermethylated genes associated with tumor resistance to cisplatin

The development of cisplatin resistance in human cancers is controlled by multiple genes and leads to therapeutic failure. Hypermethylation of specific gene promoters is a key event in clinical resistance to cisplatin. Although the usage of multiple promoters is frequent in the transcription of huma...

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Veröffentlicht in:Mol Clin Oncol
Hauptverfasser: IBRAHIM-ALOBAIDE, MOHAMMED A., ABDELSALAM, ABDELSALAM G., ALOBYDI, HYTHAM, RASUL, KAKIL IBRAHIM, ZHANG, RUIWEN, SRIVENUGOPAL, KALKUNTE S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2015
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360857/
https://ncbi.nlm.nih.gov/pubmed/25798277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2014.468
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