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Daptomycin plus fosfomycin versus daptomycin monotherapy in treating MRSA: protocol of a multicentre, randomised, phase III trial

INTRODUCTION: Despite the availability of new antibiotics such as daptomycin, methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia continues to be associated with high clinical failure rates. Combination therapy has been proposed as an alternative to improve outcomes but there is a lack of...

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Publicat a:BMJ Open
Autors principals: Shaw, E, Miró, J M, Puig-Asensio, M, Pigrau, C, Barcenilla, F, Murillas, J, Garcia-Pardo, G, Espejo, E, Padilla, B, Garcia-Reyne, A, Pasquau, J, Rodriguez-Baño, J, López-Contreras, J, Montero, M, de la Calle, C, Pintado, V, Calbo, E, Gasch, O, Montejo, M, Salavert, M, Garcia-Pais, M J, Carratalà, J, Pujol, M
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360784/
https://ncbi.nlm.nih.gov/pubmed/25762232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2014-006723
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