Demethylation of the hTERT promoter in normal human gastric mucosal epithelial cells following N-methyl-N'-nitro-N-nitrosoguanidine exposure

N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) is an alkylating agent that can induce gastric carcinoma. As a well-known human carcinogen, MNNG has been universally recognized as a methylating agent and is believed to act through methylation mechanism. In the present study, the epigenetic status o...

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Опубликовано в: :Biomed Rep
Главные авторы: CHENG, YONG-BO, FANG, DIAN-CHUN, YAO, PING, GUO, LI-PING, NING, XIAO-YAN, WANG, LEI
Формат: Artigo
Язык:Inglês
Опубликовано: D.A. Spandidos 2015
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360657/
https://ncbi.nlm.nih.gov/pubmed/25798244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2014.398
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