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Demethylation of the hTERT promoter in normal human gastric mucosal epithelial cells following N-methyl-N'-nitro-N-nitrosoguanidine exposure

N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) is an alkylating agent that can induce gastric carcinoma. As a well-known human carcinogen, MNNG has been universally recognized as a methylating agent and is believed to act through methylation mechanism. In the present study, the epigenetic status o...

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Publicat a:Biomed Rep
Autors principals: CHENG, YONG-BO, FANG, DIAN-CHUN, YAO, PING, GUO, LI-PING, NING, XIAO-YAN, WANG, LEI
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360657/
https://ncbi.nlm.nih.gov/pubmed/25798244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2014.398
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