GPR39 (Zinc Receptor) Knockout Mice Exhibit Depression-Like Behavior and CREB/BDNF Down-Regulation in the Hippocampus

BACKGROUND: Zinc may act as a neurotransmitter in the central nervous system by activation of the GPR39 metabotropic receptors. METHODS: In the present study, we investigated whether GPR39 knockout would cause depressive-like and/or anxiety-like behavior, as measured by the forced swim test, tail su...

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Bibliografiske detaljer
Udgivet i:Int J Neuropsychopharmacol
Main Authors: Młyniec, Katarzyna, Budziszewska, Bogusława, Holst, Birgitte, Ostachowicz, Beata, Nowak, Gabriel
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360246/
https://ncbi.nlm.nih.gov/pubmed/25609596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyu002
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