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Presence of rd8 mutation does not alter the ocular phenotype of late-onset retinal degeneration mouse model
PURPOSE: A spontaneous frameshift mutation, c.3481delC, in the Crb1 gene is the underlying cause of dysplasia and retinal degeneration in rd8 mice. The rd8 mutation is found in C57BL/6N but not in C57BL/6J mouse sub-strains. The development of ocular pathology in single knockout Ccl2(−/−), Cx3cr1(−/...
Kaydedildi:
| Yayımlandı: | Mol Vis |
|---|---|
| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Molecular Vision
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4360165/ https://ncbi.nlm.nih.gov/pubmed/25814825 |
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