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A compartmentalized microfluidic neuromuscular co-culture system reveals spatial aspects of GDNF functions

Bidirectional molecular communication between the motoneuron and the muscle is vital for neuromuscular junction (NMJ) formation and maintenance. The molecular mechanisms underlying such communication are of keen interest and could provide new targets for intervention in motoneuron disease. Here, we...

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Détails bibliographiques
Publié dans:J Cell Sci
Auteurs principaux: Zahavi, Eitan Erez, Ionescu, Ariel, Gluska, Shani, Gradus, Tal, Ben-Yaakov, Keren, Perlson, Eran
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359927/
https://ncbi.nlm.nih.gov/pubmed/25632161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.167544
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